Dka thesis

The complications of DKA are complications of treatment and cerebral edema. Treatment complications are hypoglycemia, hyperkalemia, and occasionally pulmonary edema. These can be avoided by using low-dose insulin therapy, monitoring blood glucose very closely, and by carefully managing fluid replacement.

Decreasing insulin dose may limit those complications. DKA treatment recommendations should take into account the type of diabetes. Diabetic ketoacidosis (DKA) is a severe acute event in diabetes mellitus characterized by dehydration, hyperglycaemia and metabolic acidosis due to ketone hyperproduction.

Obtain baseline serum electrolytes, BUN, creatinine, serum glucose, an arterial or venous blood gas (either one is appropriate), a complete blood count, an ECG, and a CXR. Consider other laboratory studies if DKA is thought to be caused by an underlying disease.

This is a French multicentre retrospective cohort study of patients admitted for DKA in five adult intensive care units in Paris and its suburb, between January 1, 2013 and December 31, 2014. All participating units were closed units.